The book constitutes the refereed proceedings of the 10th International Conference on Verification, Model Checking, and Abstract Interpretation, VMCAI 2009, held in Savannah, GA, USA, in January 2009 - co-located with POPL 2009, the 36th Annual Symposium on Principles of Programming Languages.

The 24 revised full papers presented together with 3 invited talks and 2 invited tutorials were carefully reviewed and selected from 72 submissions. The papers address all current issues from the communities of verification, model checking, and abstract interpretation, facilitating interaction, cross-fertilization, and advancement of hybrid methods that combine the three areas.